Name: GHK-Cu (Copper Peptide)
Brand: PeptiHealth
Availability: OutOfStock

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Product Usage Notice · This product is intended strictly for research and laboratory use only. It is designated for in vitro testing and experimental purposes. Any use involving human or animal consumption is prohibited by law. All information provided on this website is for educational purposes only. This product must only be handled by licensed, qualified professionals. It is not intended for use as a drug, food, or cosmetic, and must not be misused, mislabeled, or misrepresented as such. Read full Research Use Policy →

Compound Information

Technical specifications

Molecular Profile

What Is GHK-Cu (Copper Peptide)?

GHK-Cu (copper peptide) is a naturally occurring copper complex of the tripeptide Gly-His-Lys, investigated in vitro for extracellular-matrix remodeling, metalloproteinase signaling, and antioxidant pathway activity.

Type: Peptide
CAS Number: 89030-95-5
Molecular Weight: 403.9 g/mol
Amino Acids: 3 residues
Sequence: Gly-His-Lys
Formula: C14H24CuN6O4

PubChem Database

GHK-CU · 2018

Matrix-signaling and Pathway Actions of the GHK-Cu Peptide in the Light of the New Gene Data International Journal of Molecular Sciences Gene expression analysis showing GHK-Cu regulates 4,000+ human genes, upregulating matrix-signaling genes while suppressing senescence-related genes including NF-κB and inflammatory mediators.

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GHK-CU · 2015

GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in dermal matrix signaling BioMed Research International Comprehensive review demonstrating GHK-Cu stimulates collagen and elastin synthesis, modulates metalloproteinase activity, Modulates fibroblast function, and operates through multiple signaling mechanisms.

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GHK-CU · 2012

The Human Tripeptide GHK-Cu in Oxidative Stress and Aging Research Oxidative Medicine and Cellular Longevity GHK-Cu functions as a copper complex studied for its roles in tissue remodeling and collagen synthesis through angiogenesis, antioxidant defense, and protein homeostasis pathways, with age-related plasma level changes noted. Cited for scientific context only.

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GHK-CU · 2015

GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in dermal matrix signaling BioMed Research International GHK-Cu modulates expression of 4,000+ human genes, shifting gene expression patterns across antioxidant, inflammatory pathway, stem cell, and DNA remodeling pathways — characterized in vitro and in preclinical models. Cited for scientific context only.

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GHK-CU · 2012

The Human Tripeptide GHK-Cu in Oxidative Stress and Aging Research Oxidative Medicine and Cellular Longevity Published study examining age-related changes in plasma GHK-Cu levels and their correlation with oxidative stress biomarkers in preclinical and in vitro models. Cited for scientific context only; does not constitute a product claim for this research compound.

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GHK-CU · 2007

Biological Effects of a Novel Multifunctional GHK-Cu Loaded matrix model International Journal of Pharmaceutics GHK-Cu-loaded matrix models were associated with altered tissue remodeling readouts in a rat model, including changes in collagen synthesis markers, angiogenesis, and tissue remodeling cytokine expression. Findings are from animal models; cited for scientific context only.

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