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Compound reference

Cagrilintide

Metabolic Research · vial. For laboratory research use only. Not for human or veterinary consumption, diagnostic use, therapeutic use, or clinical use.

Chemistry identity

Reference identifiers

CAS 1415456-99-3Formula C194H312N54O59S2MW 4409 g/mol (computed, PubChem)PubChem CID 171397054Amino acids 37

COA documentation

Lot record status

COA per lot - on requestView Lab Reports

Published literature

Research context

Peer-reviewed literature referencing this compound, provided for research context.

Development of Cagrilintide, a Long-Acting Amylin Analogue2021

Kruse T, Hansen JL, Dahl K, Schäffer L, Sensfuss U, Poulsen C, et al.

Journal of Medicinal Chemistry

This medicinal-chemistry study reports the structure-activity and molecular-design work used to develop stable, lipidated reference cagrilintide, including sequence substitutions and terminal modifications. The publication describes the reference compound and is not verification of the identity or purity of a PeptiHealth lot.

AM833 Is a Novel Agonist of Calcitonin Family G Protein-Coupled Receptors: Pharmacological Comparison with Six Selective and Nonselective Agonists2021

Fletcher MM, Keov P, Truong TT, Mennen G, Hick CA, Zhao P, et al.

Journal of Pharmacology and Experimental Therapeutics

This receptor-pharmacology study compared reference AM833 with selective and nonselective calcitonin-family receptor agonists across binding, signaling, activation, and regulation endpoints, defining its experimental profile at amylin-receptor and CTR systems. It does not provide lot-specific analytical evidence.

Structural and dynamic features of cagrilintide binding to calcitonin and amylin receptors2025

Cao J, Belousoff MJ, Johnson RM, Keov P, Mariam Z, Deganutti G, et al.

Nature Communications

This cryo-EM and molecular-dynamics study resolved reference cagrilintide bound to active, Gs-coupled AMY1R, AMY2R, AMY3R, and CTR complexes and compared receptor engagement and conformational dynamics across the receptor family. It is reference-compound literature, not lot verification.

Structural and mechanistic insights into dual activation of cagrilintide in amylin and calcitonin receptors2026

Gu YM, Yuan QN, Li X, He Q, Xu HE, Zhao LH

Acta Pharmacologica Sinica

This structural study examined reference cagrilintide complexes with amylin and calcitonin receptors to characterize peptide-receptor contacts and activation mechanisms. The findings support receptor-structure research applications but do not establish any PeptiHealth lot result.

Catalog access requires an account and acceptance of a research-use disclaimer.

This product is intended strictly for research and laboratory use only. It is designated for in vitro testing and experimental purposes. Any use involving human or animal consumption is prohibited by law. All information provided on this website is for educational purposes only. This product must only be handled by licensed, qualified professionals. It is not intended for use as a drug, food, or cosmetic, and must not be misused, mislabeled, or misrepresented as such.