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Compound Information

Technical specifications

Molecular Profile

What Is 5-Amino-1MQ?

5-amino-1-methylquinolinium (5-A-1MQ) is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), a cytosolic enzyme that catalyzes the N-methylation of nicotinamide using S-adenosylmethionine (SAM) as methyl donor, producing 1-methylnicotinamide. By inhibiting NNMT, 5-A-1MQ is studied for its effects on NAD+ precursor flux, cellular methylation capacity, and adipogenesis pathway signaling in preclinical metabolic research models.

Type: Small molecule
CAS Number: 1148388-54-8
Molecular Weight: 158.20 g/mol
Formula: C10H10N2

PubChem Database